The postprandial transcriptomic response of adipose tissue to high fat meals in middle-aged men with metabolic syndrome

This study aimed to examine the postprandial transcriptome of adipose tissue middle-aged men selectively recruited on the basis of MetS (defined by the International Diabetes Federation (IDF) criteria) and healthy control participants. Two breakfast meals that provided different macronutrient composition, and were indicative of major patterns of dietary habits (animal-based versus plant-based) were given, postprandial adipose gene expression was measured by microarray at fasting (0 h) and 4 hours post-meal. Total RNA obtained from adipose tissue biopsies at fasting (0 h) and 4 h postprandial.