Strand-specific RNA sequencing profile of wild type and dbp2∆ strains [re-analysis]
收藏Alliance of Genome Resources2026-08-01 收录
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By comparing differentially expressed genes in dbp2∆ to those of 700 other deletion strains from other studies, we report that CYC8 and TUP1, which form a complex and inhibit transcription of numerous genes, co-repress a common set of genes with DBP2. Functional annotation clustering analysis reveals that these co-repressed genes are related to cellular metabolism. Furthermore, we find that co-repressed genes have a higher propensity to be overlapped with long non-coding RNAs at their promoter/5' regions.
