Allele and genotype frequencies of rs144169475 in the Robinson Crusoe validation cohort.

1 – Islanders who are directly related to one of the eight founder families (NB this sample includes affected andunaffected individuals)2 – Individuals who live on the Island but have no known genetic connection to the eight founder families (NB this sample includes 4 affected and 7 unaffected individuals)3 – Islanders who have been diagnosed with SLI as described in methods (NB, this sample included 45 related, founder-related individuals and 4 non-founder-related parents).4 – Islanders who have been classified as having typical language ability as described in methods (NB, this sample included 55 founder-related Islanders and 7 non-founder-related parents).5 – Male individuals who are directly related to one of the eight founder families (NB this sample includes affected and unaffected individuals)6 – Female individuals who are directly related to one of the eight founder families (NB this sample includes affected and unaffected individuals)7 - 127 in-house European controls (ECACC, HRC-1 DNA Panel)8 - 320 South American (Colombian) controls (provided by Luis Carvajal-Carmona and Maria Magdalena Echeverry)9 – 121 Chilean controls (provided by Lillian Jara and Pia Villanueva)10 – 1000 genomes Puerto Ricans from Puerto Rico (Integrated phase I, accessed March 2014)11 – 1000 genomes Colombians from Medellin, Colombia (Integrated phase I, accessed March 2014)12 – 1000 genomes Mexican Ancestry from Los Angeles USA (Integrated phase I, accessed March 2014)Allele and genotype frequencies of rs144169475 in the Robinson Crusoe validation cohort.