Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production

NIAID Data Ecosystem2026-03-10 收录

骨形成机制

成骨细胞分化

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https://www.omicsdi.org/dataset/bioimages/S-JCBD-201002111 数据链接链接失效反馈

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Micro-CT and von Kossa staining of spines at 3 mo. Bar, 500 μm

创建时间：

2018-11-29

Osteoprotection through the deletion of the transcription factor Rorβ in mice

成骨细胞分化

基因功能研究

Purpose: To identify gene expression changes (using RNAsequencing) in MC3T3-E1 cells where Rorβ has been deleted using CRISPR/Cas9 (and a control cell line) Method: MC3T3-Control and MC3T3-Rorβ-CRISPR

NIAID Data Ecosystem110

Expression data from human adipose tissue-derived mesenchymal stem cells

成骨细胞分化

基因表达谱分析

miR-375 play an important role in regulating the osteogenesis in human adipose tissue-derived mesenchymal stem cells, following specific genes are up-regulated or down-regulated. We used microarrays t

NIAID Data Ecosystem50

Activating PIK3CA mutation promotes osteogenesis of bone marrow mesenchymal stem cells in macrodactyly

巨指症发病机制

成骨细胞分化

Comparison of differential expression between macrodactyly BMSC and polydactyly BMSC Total RNAs was extracted from passage 3 of cultured Macrodactyly-BMSCs (n=2) and Polydactyly-BMSCs (n=2) ,complemen

NIAID Data Ecosystem40

Osteoblast differentiation experiment: BMP-2 induced osteogenesis in mouse MC3T3 cell line. Mus musculus

成骨细胞分化

基因表达分析

MC3T3 cells clone 1b were grown in alpha-MEM with 10% fetal calf serum (FCS, Gibco), 1% penicilin/streptomycin (Pen/Strep) and 1% L-Glutamine (L-Glu). For differentiation experiment, cells were seeded

NIAID Data Ecosystem70

Priming integrin alpha5 promotes human mesenchymal stromal cell osteoblast differentiation and osteogenesis

成骨细胞分化

骨再生治疗策略

Human adult mesenchymal stromal cells (hMSC) have the potential to differentiate into chondrogenic, adipogenic or osteogenic lineages, providing a potential source for tissue regeneration. An importan

NIAID Data Ecosystem50

Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production

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