N6-methyladenosine (m6A) methylation is associated with immune homeostasis in acute intracerebral hemorrhage(ICH)

NIAID Data Ecosystem2026-03-13 收录

RNA表观遗传学

神经免疫调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA837424 数据链接链接失效反馈

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资源简介：

To explore the differential methylation modification in ICH patients.

创建时间：

2022-05-12

List of upregulated genes.

神经免疫调控

单细胞转录组学

Microglia, the resident immune cells of the brain, are crucial in the development of the nervous system. Recent evidence demonstrates that microglia modulate adult hippocampal neurogenesis by inhibiti

NIAID Data Ecosystem50

m6A IP sequencing analysis of m6A mRNA methylation regulation by FTO in melanoma cells. m6A IP sequencing analysis of m6A mRNA methylation regulation by FTO in melanoma cells

RNA表观遗传学

黑色素瘤分子机制

N6-methyladenosine (m6A) RNA methylation is the most abundant internal chemical modifications in eukaryotic messenger RNA (mRNA) as well as long non-coding RNA (lncRNA). Recently, m6A RNA methylation

NIAID Data Ecosystem50

Open chromatin landscape of rat microglia upon inflammatory or pro-invasive polarization

神经免疫调控

染色质可及性分析

Microglia are brain-resident, myeloid cells that play important roles in health and brain pathologies. While data on chromatin accessibility in activated murine microglia are available, there is no su

NIAID Data Ecosystem30

Targeting tumor-intrinsic N7-methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy. Targeting tumor-intrinsic N7-methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy

肿瘤免疫治疗

RNA表观遗传学

We found that PMN-MDSCs level is elevated in the advanced ICCs tissues and is positively associated with the METTL1 and m7G tRNA modification levels. We further showed that impaired m7G tRNA modificat

NIAID Data Ecosystem50

RNA m6A modification mediated by METTL3 is important for IAP heterochromatin integrity in mESCs (MeRIP-Seq)

RNA表观遗传学

细胞染色质调控

N6-methyladenosine (m6A) methyltransferase METTL3 mainly mediates mRNA m6A methylation and plays important roles in various biological processes. Here we report a chromatin-based role for METTL3 in he

NIAID Data Ecosystem50

N6-methyladenosine (m6A) methylation is associated with immune homeostasis in acute intracerebral hemorrhage(ICH)

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