Chan-Soo Lee, Chang-Ki Choi, Eun-Young Shin, Martin Alexander Schwartz, Eung-Gook Kim (2011) CIL:26551, Mus musculus, fibroblast. CIL. Dataset

To study the molecular mechanism by which nonmuscle myosin II (MII) regulates protrusion and adhesion dynamics in migrating cells, Swiss3T3 cells were co-stained for TRIO (green) and myosin IIA (red). These findings help elucidate a functional link between MII and Rac1/Cdc42 GTPases, which may regulate protrusion/adhesion dynamics in migrating cells. This image is the original data file from Fig. 2F “colocalization of MII with GEFs”, J. Cell Biol. 2010. Vol. 190(4):663–674.

为探究非肌肉肌球蛋白II（MII）调控迁移细胞突起和粘附动态的分子机制，Swiss3T3细胞同时进行了TRIO（绿色）和肌球蛋白IIA（红色）的共染色。本研究结果有助于阐明MII与Rac1/Cdc42 GTP酶之间的功能联系，这些酶可能调节迁移细胞中的突起/粘附动态。本图是该研究图2F“MII与GEFs共定位”的原数据文件，来源于《细胞生物学杂志》2010年第190卷第4期，页码663-674。