Forward genetic screens in Mus musculus have proved powerfully informative by revealing unsuspected mechanisms governing basic biological processes. This approach uses potent chemical mutagens, such
Number of cells in each experiment from each cell type and organ source are indicated in brackets. Only cells which participated in lineage analysis are shown. % Amp. = percent of alleles which were s
Variant effect predictions used in the publication: Genomic analyses implicate noncoding de novo variants in congenital heart disease All variants are specified in hg19 coordinates
The numbers are the percentages of non-reference alleles as defined by the Cambridge Reference Sequence, NC_012920.1. The “-” denotes no heteroplasmy detected above the threshold of 1%.