Microarray for duodenum epithelium of C57Bl6 PPARgVillinCRE and wild type mice submitted to 2 weeks 75% caloric restriction compared to ad libitum fed controls

The experiment aims at a characterization of gene expression changes in duodenum during caloric restriction. The C57BL6 mice were restricted their food intake to 75% of their normal daily portion. The food was delivered daily around 4-6pm for 14 days. The mice were housed with free access to water. The control age-matched mice were fed ad libitum. The publication associated with this dataset concerns WT mice only. However, the experiment and microarray data normalization was performed for samples of WT and PPARgVillinCRE mice together. Thus for analysis reproducibility reasons data of all samples is made available.本实验旨在探究热量限制（caloric restriction）过程中小鼠十二指肠内的基因表达变化特征。实验将C57BL/6小鼠的每日进食量限制为正常每日摄食量的75%，每日于下午4至6点左右投喂食物，实验周期共计14天。所有小鼠可自由获取饮水。同年龄段的对照组小鼠采用自由采食（ad libitum）方式喂食。本数据集关联的发表论文仅涉及野生型（Wild Type, WT）小鼠，但本实验及基因芯片（microarray）数据标准化流程同时针对野生型与PPARgVillinCRE小鼠的样本开展。因此，为保障分析结果的可重复性，本数据集公开了所有样本的检测数据。