Additional file 4. Data S1. List of exonic alleles that undergo somatic selection (P < 0.05) with estimated selection pressure (Pi) and affected gene in four TCGA cancer types, BRCA, LUAD, COAD and PR
DNA and Histone-3 Lysine 27 methylation typically function as repressive modifications and operate within distinct genomic compartments. In mammals, the majority of the genome is kept in a DNA methyla
Table S9. Genes with significant integrated gene expression and methylation scores by SMITE analysis in transcriptional clusters 2 and 3. (XLSX 86Â kb)
We present a novel approach that leverages Oxford Nanopore direct RNA sequencing technology to detect allele-biased patterns of N6-methyladenosine (m6A) modifications in native mRNAs. Our approach uti
