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CFTR is a tumor suppressor gene in murine and human intestinal cancer [RNA-seq]

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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Analysis of the cystic fibrosis gene Cftr in the colon and small intestine of Cftr-deficient murine model. The hypothesis was loss of Cftr altered expression of genes important in intestinal homeostasis and oncogenic signaling pathways. The results identified potential roles of Cftr in up- or down-regulating major gene clusters that belong to groups of immune response, ion channel, intestinal stem cell and other growth regulators.

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2022-02-20
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