Lewis Acid Catalyzed Regiospecific Cross-Dehydrative Coupling Reaction of 2‑Furylcarbinols with β‑Keto Amides or 4‑Hydroxycoumarins: A Route to Furyl Enols
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Lewis acid catalyzed directly dehydrative carbon–carbon bond formation reaction of 2-furylcarbinols with β-keto amides provides a straightforward method for regioselective synthesis of (Z)-furyl enols. Moreover, this Lewis acid catalyzed cross-coupling reaction can be extended to an interesting heterocyclic version featuring a functionalized 3-furyl-4-hydroxycoumarin synthesis.
创建时间：
2016-06-13
