Microbiota composition in Anorexia Nervosa patients before and after weight gain as compared to healthy controls

The aim of this study was to study i) to what extend the microbiota of AN is perturbed in comparison to NW and ii) whether these perturbations are recovered after weight gain and/or normalisation of eating behaviour. In this study we have comprehensively analysed the gut microbiota (by sequencing of the V4 region of the 16S rRNA gene using MiSeq PE250) and short-chain fatty-acids (SCFA) profile in stool samples of AN patients ahead (n=55) and after weight gain (n=44) in comparison to normal-weight participants matched for age and gender (NW, n=55).