Crystal structure of monkey TLR7 ectodomain with compound 20
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Crystal structure of monkey TLR7 ectodomain with compound 20 Descriptor: (3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Critton, D.A. Deposit date: 2023-08-15 Release date: 2024-02-07 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.14 Å) Cite: Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology. Acs Med.Chem.Lett., 15, 2024
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2023-08-15
