Mayo Clinic Adult Diffuse Glioma Illumina OncoArray SNP Data

These data are from adult diffuse glioma subjects genotyped on the Illumina OncoArray. Data from this study were used for case control association studies and developing polygenic risk scores. Variants in D2HGDH and near FAM20C were identified that were associated with glioma subtypes (PMID: 32386320). Mutation and copy number data are included for select genes and chromosomes. IDH mutation and 1p/19q co-deletion are used in glioma diagnosis and are also prognostic markers. Data for additional prognostic genes and chromosomes are also included. RNA-seq and CHIP-seq data are available for select subjects from this cohort in GEO (GSE167806).]]>
Inclusion CriteriaAll subjects were pathologically confirmed to have glioma. Subjects had to be consented at 18 years of age or older. All subjects provided a germline DNA sample.]]>