Adrenomedullin promotes the migration of interneurons in a human forebrain assembloid model for hypoxic interneuronopathy of prematurity.
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE183201
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We developed a model for hypoxic injury of migrating human cortical interneurons using forebrain organoids and forebrain assembloids derived from hiPSCs. Human subpallial organoids at day 46 in culture were exposed to hypoxia (<1% oxygen) for 12 and 24 hours. Some samples were exposed for 24 hours and subsequently reoxygenated for 72 hours. Samples were immediately collected and snap frozen for processing.
创建时间：
2023-09-01
