Supporting data for "Dysregulation of Ral GTPase-Activating Protein Complex activates RalA signaling and supports metastasis of hepatocellular carcinoma through intrinsic and extracellular vesicle-dependent manners"
收藏datahub.hku.hk2021-09-24 更新2025-01-09 收录
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https://datahub.hku.hk/articles/dataset/Supporting_data_for_Dysregulation_of_Ral_GTPase-Activating_Protein_Complex_activates_RalA_signaling_and_supports_metastasis_of_hepatocellular_carcinoma_through_intrinsic_and_extracellular_vesicle-dependent_manners_/16601255/1
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资源简介:
This dataset contains the function of RalGAP complex and RalA in HCC. It includes the clinical analysis if qPCR, RNA-sequencing, and targeting sequencing of HCC patients. The RalA and RalGAP manipulated cells confirmation and functional assays were included. In addition, a specific inhibitor RBC8 was invesgated in vitro and in vivo. Also, the sEV related information and functional assays with RalA manipulation was included. Lastly, all animal models and data were included.
本数据集涵盖了RalGAP复合体及其在肝细胞癌(HCC)中作用的函数。其中包含了针对HCC患者的临床分析,包括qPCR、RNA测序和靶向测序。数据集还包括了通过操纵RalA和RalGAP实现的细胞验证和功能实验。此外,还对体外和体内实验中使用的特定抑制剂RBC8进行了研究。同时,还纳入了与RalA操作相关的sEV相关信息和功能实验。最后,数据集包含了所有动物模型及其相关数据。
提供机构:
HKU Data Repository



