Legionella pneumophila, an environmental bacterium that parasitizes protozoa, is the causative pathogen of Legionnaires' disease. L. pneumophila adopts a distinct biphasic life cycle that allows it to

NIAID Data Ecosystem20

Cell cycle arrest mediates the fate of embryonic neural progenitor cells. Mus musculus

神经细胞命运决定

细胞周期调控

Neural stem cells (NSCs) in the adult mouse brain regulate innate and adaptive behaviors and represent an important system to understand mechanisms of neurogenesis. Adult NSCs in the subventricular zo

NIAID Data Ecosystem20

RNA sequencing (RNA-Seq)-based transcriptomic analysis in shCNN2 and shCtrl A549 cells

基因功能研究

细胞周期调控

In the present study, the multi-omics analysis of A549 cells transduced with shCtrl or shCNN2 revealed that CNN2 may play a role in regulating actin cytoskeleton-mediated DNA replication and cell cycl

NIAID Data Ecosystem10

Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry

细胞周期调控

有丝分裂进入机制

The Cdc25A phosphatase is an essential activator of CDK-cyclin complexes at all steps of the eukaryotic cell cycle. The activity of Cdc25A is itself regulated in part by positive and negative feedback

Taylor & Francis Group2016-09-27 更新20

mRNA of the G1/S repressor WHI5 is found at similar levels throughout the cell cycle

细胞周期调控

RNA定量

While it is clear that cells need to grow before committing to division at the G1/S transition of the cell cycle, how cells sense their growth rate or size at the molecular level is unknown. It has be

NIAID Data Ecosystem10

Supporting Data 5 (Data S5): Raw LxCxE amino acid sequences

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