COUP-TFII Controls Mouse Postnatal Pancreatic ß-Cell Mass through GLP-1 ß-Catenin
收藏Alliance of Genome Resources2026-08-01 收录
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Conclusions/significance: Our findings show that COUP-TFII is a novel component of the GLP-1 signaling cascade that increases b-cell number during the neonatal period. COUP-TFII is required for GLP-1 activation of the b-catenin-dependent pathwayand its expression is under the control of TCF7L2.
