10-Marker Haplotype Clusters and Family-Based Test of Association with Psoriasis.

NOTE��The table displays all 9 markers subjected to haplotype clustering, along with HLA-B, in centromeric��telomeric order, from left to right. Italicized numbers indicate that the allele occurred in 50%�C80% of the founder haplotypes comprising the cluster. Numbers in roman type indicate that the allele occurred in at least 80% of the founder haplotypes comprising the cluster. The alleles for HLA-B and CDSN are standard allele designations, whereas for HLA-C, 2 correspond to Cw6 alleles, and 1 corresponds to non-Cw6 alleles. The bold number area shows the minimum region of conserved by all risk haplotypes.aAll clusters among 699 founder chromosomes genotyped in 163 pedigrees are shown.bFrequency of haplotypes in cluster.cFor the biallelic TDT.dUncorrected exact binomial P value for TDT.