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Effective Extracellular Payload Release and Immunomodulatory Interactions govern the Therapeutic Effect of Trastuzumab Deruxtecan (T-DXd)

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Figshare2025-04-03 更新2026-04-08 收录
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https://springernature.figshare.com/articles/dataset/Effective_Extracellular_Payload_Release_and_Immunomodulatory_Interactions_govern_the_Therapeutic_Effect_of_Trastuzumab_Deruxtecan_T-DXd_/27919128
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资源简介:
Immunohistochemistry assessment of tumor infiltrating T cells levels and spatial location. CD8+ (brown), CD4+ (blue) and FoxP3+ (red). Tumors were from HER2 oncogene driven transgenic mice, and treatment were administered weekly for 4 weeks, 5.4mg/kg control IgG1, 5.4mg/kg T-DXd, and 15mg/kg anti-CD47 (MIAP410)
提供机构:
Sodhi, Sirajbir; Wang, Tao; Yang, Xiao; Lei, Gangjun; McBane, Jason; Trotter, Timothy; Spasojevic, Ivan; Wang, John; Ma, Xingru; Liu, Bushanqing; Morse, Michael; Liu, Cong-Xiao; Hartman, Zachary; Tsao, Li-Chung; Wei, Junping; Lyerly, Herbert; Fan, Ping; Ragusa, Joey
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2025-04-03
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