SpaceX Inspiration4 Blood Serum Metabolic Panel and Immune/Cardiac Cytokine Arrays (Comprehensive Metabolic Panel and Multiplex)

The SpaceX Inspiration4 mission was a 3-day mission with four private astronauts to low Earth orbit that occurred in September 2021. The crew collected biospecimen samples before, during, and after flight. One of these biospecimen collections included whole blood collected via venipuncture, with serum extracted from blood using a serum separator tube (SST). Samples were collected pre-flight (L-92, L-44, L-3) and post-flight (R+1, R+45, R+82). Serum samples were submitted for immune and cardiovascular cytokine biomarker profiling panels at two different companies (Eve Technologies and Alamar), and to Quest Diagnostics for comprehensive metabolic panel testing. Data was used to measure changes in cytokines and metabolic measures during spaceflight. This study derives results from the Comprehensive Metabolic Panel and Multiplex assays, and the blood serum data in this study are related to other studies using data from the same experiment; OSD-569 (whole blood), OSD-570 (peripheral blood mononuclear cells), OSD-571 (plasma), OSD-572 (skin, oral, and nasal swabs), OSD-573 (Dragon capsule samples), OSD-574 (skin biopsy), OSD-656 (urine), and OSD-630 (stool).