Peak allelic associations within genomic regions of sarcoidosis ancestry linkage after adjustment for both global and local West African ancestry and corresponding MIX score results.

Abbreviations: fCEU: frequency of modeled allele in HapMap Northern and Western European ancestry population; fAFR: frequency of modeled allele in HapMap Yoruban African ancestry population; fAFF: frequency of modeled allele in sarcoidosis-affected individuals; fUNF: frequency of modeled allele in unaffected individuals; OR: odds ratio; 95%CI: 95% confidence interval; P: p-value; MIX: MIXSCORE test.1Minor allele in African Americans is bolded; modeled by generalized estimating equations adjusting for percent global West African ancestry and sex.2“Imputed” Indicates a SNP that was imputed rather than directly genotyped. Accuracy of imputation was assessed for SNPs with p-values−5 in a sub-sample, and for each SNP; agreements overall and by genotype are reported in Table S2. Overall accuracy of imputation was 98.7% (rs62158012) and 98.0% (rs6502976).3No carriers of the T allele of rs78512816 exist within HapMap and 1000 Genomes Project European populations.