Shown are mean values calculated from at least three experiments ± SD. The cytotoxicity values (CC50) were for Hela H cells 8.54 ± 0.42 μM, for Hela R19 cells 7.07 ± 0.38 μM, and for RD, BGM, and Vero
Table 3 Biological activities of isolated Vinca minor alkaloids. CompoundIC50 h AChE ± SEM (μM) aIC50 h BuChE ± SEM (μM) aIC50 POP ± SEM (μM) a% inhibition of GSK-3β SEM b ±logBB cPAMPA (P e; 10 6 cm