Abcc6

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein is unknown; however, a similar rat protein has been identified as the major canalicular bile salt export pump of liver. [provided by RefSeq, Jul 2008]

该基因编码的蛋白质属于ATP结合盒（ABC）转运蛋白超家族。ABC蛋白负责将各种分子跨越细胞内外膜进行运输。ABC基因可分为七个不同的亚家族（ABC1、MDR/TAP、MRP、ALD、OABP、GCN20、White）。该蛋白质是MRP亚家族的成员，该亚家族参与多重耐药性。该蛋白质的具体功能尚不明确；然而，一种类似的大鼠蛋白质已被确认为肝脏主要胆盐分泌泵。资料来源：RefSeq，2008年7月。