Triploid causes genome instability in tumorigenesis
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32449
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To examain effects of triploidy on gene expression in mouse cells, we have employed whole genome microarray expression profiling. To study the effects of aneuploidy in mouse cells, we isorated diploid, triploid and tetraploid cells from p53-/- mouse embryonic cells Gene expression in diploid cells (RRI2, 15 and 2-1), triploid cells (RRI2-5, 2-12 and 2-15) and tetraploid cells (RRI2-2, 2-4 and 2-6).
创建时间:
2018-02-02



