Fragment based discovery and optimisation of bace-1 inhibitors
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Fragment based discovery and optimisation of bace-1 inhibitors Descriptor: (3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]pentanamide, Beta-secretase 1, IODIDE ION Authors: Madden, J, Godemann, R, Smith, M.A, Hallett, D, Barker, J, Kraemer, J. Deposit date: 2011-05-17 Release date: 2011-06-01 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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2011-05-17
