The change in the expression level and/or pattern of target genes in Irx7 knockdown experiments.

The expression level and/or pattern of the candidate target genes were determined from representative irx7SMO morphants and controls. The resulting regulatory relationship between Irx7 and these candidate genes was also inferred by comparing these two sample groups. See Figure 11 for the resulting network, Figure S2 for the comprehensive network that also includes additional connections of the candidate genes as extracted from literature references (File S2).