CRISPR systems are widespread in the prokaryotic world, providing adaptive immunity against mobile genetic elements (MGE) 1,2. Type III CRISPR systems, with the signature gene <st
K78 acetylation inhibits the global outcome of DasR binding to its targeted genes in vivo. Overall design: Saccharopolyspora erythraea WT and K78Q strains grown in TSB medium are used for ChIP-seq
This proposal is a collaborative effort of the Macromolecular Structural Biology Groups in Valencia –six at the Instituto de Biomedicina de Valencia (IBV-CSIC) and one at the University of Valencia– w