Palladium Catalyzed Asymmetric Allylation of 3‑OBoc-Oxindoles: An Efficient Synthesis of 3‑Allyl-3-hydroxyoxindoles
收藏数据链接：
官方服务：
资源简介：
3-Allyl-3-hydroxyoxindoles were synthesized in very good enantio- (up to 97% ee) and diastereoselectivities (dr up to 7.6:1) with contiguous quaternary and tertiary stereogenic centers by employing tartrate derived bi(oxazoline) in Pd-catalyzed allylation of 3-OBoc-oxindole. Synthetic utility of 3-allyl-3-hydroxyoxindole was demonstrated by synthesizing a highly substituted spiro(oxindole-3,2′-tetrahydrofuran) derivative in good yield and stereoselectivity.
创建时间：
2016-02-14
