Long-term persistence of exhausted CD8 T cells in chronic infection induced by microRNA-155

Mendeley Data2018-03-24 更新2026-04-09 收录

T细胞耗竭

MicroRNA调控

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miR-155 promotes exhaustion of CD8 T cells by targeting Fosl2.

创建时间：

2018-03-24

Analysis of microRNA expression during Epstein-Barr virus encoded LMP1 and LMP2A transfected in TW03 cells. Homo sapiens

病毒致癌机制

MicroRNA调控

Epstein-Barr virus has been reported to regulate cellular microRNA expression in B cells. In the present study, we investigated the differential microRNAs modulated by Epstein-Barr virus in Naspharyng

NIAID Data Ecosystem90

RNA-Seq analysis of P14 CD8+T cells in B16-GP tumors

肿瘤浸润T细胞

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CD8+ T cells play an important role in fighting against tumors. However, CD8+ T cells often become functionally impaired or “exhausted” in the tumor microenvironment. T cell exhaustion is a major hurd

NIAID Data Ecosystem60

Maternal recognition of pregnancy in the horse: are microRNAs the secret messengers? [RNA-seq]

马妊娠识别

MicroRNA调控

The signal for maternal recognition of pregnancy (MRP) has still not been identified in the horse. Endometrial biopsies, uterine fluid, embryonic tissues and yolk sac fluid were collected 13 days afte

NIAID Data Ecosystem50

Anti-miRs Competitively Inhibit microRNAs in Argonaute Complexes

MicroRNA调控

寡核苷酸药物作用机理

MicroRNAs (miRNAs), small RNA molecules that post-transcriptionally regulate mRNA expression, are crucial in diverse developmental and physiological programs and their misregulation can lead to diseas

NIAID Data Ecosystem90

scRNA-seq of antigen-specific CD8+ T cells from tumor draining LN, TIL and PBMC of melanoma bearing mice

肿瘤免疫

T细胞耗竭

CD8+ T cell-mediated immune response plays a pivotal role in controlling tumor growth.However, within the tumor microenvironment (TME), prolonged antigen exposure, as well as immunosuppressive factors

NIAID Data Ecosystem60

Long-term persistence of exhausted CD8 T cells in chronic infection induced by microRNA-155

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