Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5176
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Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5176 Descriptor: 2-{[4-(diethylamino)piperidin-1-yl]methyl}-6-iodo-4-(3-phenoxyprop-1-yn-1-yl)phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION Authors: Joerger, A.C, Wilcken, R, Fersht, A.R, Boeckler, F.M. Deposit date: 2012-01-30 Release date: 2012-03-21 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
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2012-01-30
