miRNAs predicted to target differentially expressed mRNAs using GSEA.

Using our list of differentially expressed mRNAs, we predicted which miRNAs would be upstream inhibitors with the Molecular Signatures Pathways Database (MSigDB). The overlap between the MSigDB output and our miRNA-Seq data highlighted 21 miRNAs that were differentially expressed in SLKK compared to SLK cells. Columns identify their names, the target sequence used to identify base complementarity with the input mRNA, the total number of putative target genes for a given miRNA, the number of putative targets that overlap with our input mRNA list, the percentage ratio between the overlap and the total number of putative targets, and its associated P-value and false discovery rate (FDR), correcting for multiple hypothesis testing.miRNAs predicted to target differentially expressed mRNAs using GSEA.