Supplemental Material for Bitarello and Mathieson, 2020

File_S1 is a pdf and contains 14 supplementary figures and their captions.Table S1 is an excel spreadsheet and one caption sheet and 20 sheets with content, as described below:Sheets 1-6: Different SNP sets generated by clumping and their PRS values. Effect sizes from 360K European ancestry individuals from the UK Biobank. Data from genotype arrays. Sheets 6-12: Different SNP sets generated by clumping and their PRS values. Effect sizes estimated from ‘White British’ sibling pairs from the UK Biobank. Data from genotype arrays. Sheet 13: Different SNP sets generated by clumping and their PRS values. Data from imputed datasets. Sheets 14-19: Different SNP sets generated by clumping and their unweighted PRS values. Sheet 20: Difference between PRS values for 1000G super-populations (Africa, Europe) for different sets of SNPs.

文件S1为一份PDF文档，其中包含14幅补充图及其标题。表S1为Excel电子表格，包含一个标题页及20个工作表，具体内容如下：工作表1-6：由聚类分析生成的不同SNP集及其PRS值。来自英国生物样本库的360K欧洲血统个体的效应值。数据源自基因型芯片。工作表6-12：由聚类分析生成的不同SNP集及其PRS值。从英国生物样本库的‘白英’同胞对中估算的效应值。数据源自基因型芯片。工作表13：由聚类分析生成的不同SNP集及其PRS值。数据源自推算数据集。工作表14-19：由聚类分析生成的不同SNP集及其未加权PRS值。工作表20：针对1000G超人群（非洲、欧洲）不同SNP集的PRS值差异。