Hand2-Induced Preservation of Sympathetic Neurons Prevents Sarcopenia with Aging
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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We examined age-dependent expression of the heart and neural crest derivative 2(Hand2), a critical transcription factor for post mitotic maintenance of SNs, and tested the possibility that inducing its expression exclusively in SNs will significantly prevent (a) motor denervation, (b) impaired NMJ transmission, and (d) loss of muscle mass and function in old mice
提供机构：
Oklahoma Medical Research Foundation
创建时间：
2022-02-20
