Additional file 4: of First and second trimester urinary metabolic profiles and fetal growth restriction: an exploratory nested case-control study within the infant development and environment study

Binned spectrum line using total area normalization. All NMR spectra were uploaded into the software program Chenomx NMR suite 8.2. The spectral region δ 0.5 to 9.4 ppm was divided in 216 custom bins, with region 4.69â 4.86 containing residual water resonances excluded. The bin integrals were normalized to total peak area and subsequently used for statistical analysis. (XLSX 703 kb)