Univariate linear regression analysis on putative risk factors for radiographic progression: non-genetic and genetic factors.

*Alleles shown as major allele/minor allele.†PACPA, anti-citrullinated peptide antibody; RF, rheumatoid factor. MAF; Minor allele frequency in the tested population, SE, shared epitope; PADI4, peptidyl arginine deiminase type IV; TNFAIP3, tumor necrosis factor, alpha-induced protein 3; CCR6, C-C chemokine receptor type 6; B3GNT2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2; ANXA3, annexin A3; CSF2, colony stimulating factor 2; CD83, CD83 molecule; NFKBIE, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon; ARID5B, AT rich interactive domain 5B [MRF1-like]; PDE2A, phosphodiesterase 2A, cGMP-stimulated; ARAP1, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1; PLD4, phospholipase D family, member 4; PTPN2, protein tyrosine phosphatase, non-receptor type 2.