Bystander TN_Metabolomics

Name: Bystander TN_Metabolomics
Creator: Namit Holay
Published: 2026-04-09T12:25:42+08:00

Mendeley Data2026-04-09 收录

免疫代谢

细胞代谢重编程

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资源简介：

Metabolomics analysis of bystander activated naive CD8 mouse T cells after virus exposure. In this dataset we aimed to characterize the metabolic signatures that drive the induction of bystander activated naive CD8 T cells when compared to naive CD8 T cells 1 day post exposure to virus.

提供机构：

Namit Holay

DataSheet_1_Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.zip

免疫代谢

PD-1联合治疗

IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows s

NIAID Data Ecosystem30

RNA-seq analysis reveals immune-metabolic dysregulation in DNASE1L3 knockout mice

基因敲除小鼠转录组

免疫代谢

RNA-seq was performed on liver tissues of DNASE1L3 knockout mice and wild-type controls to investigate immune and metabolic dysregulation. Paired-end sequencing was performed on Illumina NovaSeq 6000.

NIAID Data Ecosystem00

Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity

细菌癌症疗法

免疫代谢

Bacterial cancer therapy (BCT) is a promising therapeutic for solid tumours. Salmonella enterica Typhimurium (STm) is well-studied amongst bacterial vectors due to advantages in genetic modification a

NIAID Data Ecosystem00

Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans.

免疫代谢

B细胞发育

Transcriptional profiling of transitional and follicular B cells showed that metabolic quiescence was acquired at the follicular B cell stage in both humans and mice, characterized by an orchestrated

NIAID Data Ecosystem10

Transcriptional changes in human natural killer cells derived from umbilical cord blood in response to the BCL-2 inhibitor Venetoclax. Transcriptional changes in human natural killer cells derived from umbilical cord blood in response to the BCL-2 inhibitor Venetoclax

NK细胞治疗

免疫代谢

Natural killer (NK) cell-based immunotherapy holds promise for cancer treatment, but its efficacy is still limited, necessitating the development of new strategies. Here, we report an unexpected disco

NIAID Data Ecosystem00

Bystander TN_Metabolomics

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