Age-stratified Longitudinal Analysis of Hypertension Stages and Pulse Pressure Tertiles on Cognitive Decline.

Reference group for HTN: Control group (SBP≤139 mmHg): for PP: pulse pressure lower tertile (48–68 mmHg).HTN Stage I = Hypertension Stage I (SBP 140–159 mmHg); HTN Stage II = Hypertension Satge II (SBP≥160); PP middle tertile = Pulse pressure 71–77 mmHg, and PP upper tertile = Pulse pressure 84–108 mmHg.Model 1: age, race, education.Model 2: age, race, education, history of high blood pressure, stroke, myocardial infarction, congestive heart failure, peripheral artery disease, diabetes mellitus, angina; history of smoking, BMI, ever on hypertensive medication, glucose, cholesterol, and depression score.Note: All Trails B models adjust for Trails A performance.MMSE = Mini Mental State Exam; TMT, Part A = Trail Making Test, Part A; TMT, Part B = Trail Making Test, Part B; HVLT = Hopkins Verbal Learning Test (HVLT-I = immediate recall; HVLT-D = delayed recall);*p-value**p-value