Additional file 15 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

Additional file 15: Table S11. Results of the associations between CpG sites and expression of transcripts of genes codifying for enzymes or proteins directly involved with lipoprotein metabolism. Results are shown for those pairs passing a false discovery rate (Benjamini-Hochberg) threshold of FDR < 0.05. Presented are the CpG sites and expression probe IDs; the annotated genes of the CpG site and expression probe; the chromosomes of the CpG site and expression probe; the chromosomal location of the CpG site; the distance between the CpG site and expression probe (where Inf indicates they are on different chromosomes); the coefficient (Coef) of the CpG site from the regression analysis; standard error of the coefficient (SE); p value of the coefficient (P); Bonferroni-corrected p value (Bonf_P); FDR-corrected p value (FDR); number of observations for the model (N); and whether the association is significant at Bonferroni-corrected threshold (based on 12 CpGs × 62 expression probes: p < 0.05/(12 * 62) =6.7e−5 ). All coefficients are change in log2- transformed expression intensity per unit increase in methylation (beta value on 0–1 scale).