Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 1-((6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea
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Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 1-((6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea Descriptor: 1-[(6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea, Beta-glucuronidase Authors: Wallace, B.D, Redinbo, M.R. Deposit date: 2010-02-05 Release date: 2010-11-17 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. Science, 330, 2010
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2010-02-05
