Gene expression in Tbr2 lineage neurons in the murine cerebral cortex. Gene expression in Tbr2 lineage neurons in the murine cerebral cortex

During cortical development neurons are generated from basal progenitors (BPs) which specifically express the transcription factor Tbr2. We used fluorescent-activated cell sorting (FACS) to isolate Tbr2-lineage neurons (GFP+) from mice brain at postnatal day 2 (P2) and determined mRNA expression profiles using microarray (Illumina MouseWG-6 v2). Role of transcription factor Tbr2 in neurodevelopment. Overall design: FACS isolated Tbr2-lineage neurons (GFP+) from mouse brain cortex at P2 were used for microarray analysis.