RNA-Seq expression analysis of thymic epithelial cells (TEC) lacking expression of Hoil
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE139898
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To investigate the role of LUBAC in the development and maintenance of the thymic epithelail cells, we analysed the transcriptional changes that result from loss of HOIL - a critical component of the LUBAC protein complex rnecessary for complex assembly, stability and therefore function - in purified mouse thymic epithelial cell populations. RNA was isolated from freshly purified cortical and medullary thymic epithelial cells of control mice (Foxn1cre+/+ Hoillox/lox) and mice carrying TEC-specific deletion of Hoil (Foxn1creT/+ HOILlox/lox) for comparison by RNA-Seq.
创建时间:
2022-01-31



