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Transcription profiling of human synovial fibroblasts from rheumatoid arthritis and osteoarthritis patients

ChEBI2009-04-28 更新2026-07-21 收录

关节炎基因表达

滑膜成纤维细胞研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-7669 数据链接链接失效反馈

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资源简介：

Transcription profiling of human synovial fibroblasts from rheumatoid arthritis and osteoarthritis patients

应用场景：

创建时间：

2009-04-28

关节炎基因表达

RNA测序分析

Osteoarthritis (OA) is the most prevalent joint disease with the typifying feature being the progressive degradation of articular cartilage during disease progression. In this study we used whole tran

NIAID Data Ecosystem110

RNA-Seq approaches to understand the role of ARNO/Cyth2 on IL-1beta-stimulated synovial fibroblasts.. RNA-Seq approaches to understand the role of ARNO/Cyth2 on IL-1beta-stimulated synovial fibroblasts.

滑膜成纤维细胞炎症机制

关节炎基因表达

The aim of this study was to explore the role of ARNO, also known as Cyth2, in synovial fibroblasts using NGS-derived transcriptome analysis (RNA-seq). Synovial fibroblasts were isolated from mouse sy

NIAID Data Ecosystem100

Genes identified in robust genome wide approaches with fold-changes and P-values for OA versus preserved cartilage (OA vs P).

关节炎基因表达

软骨差异基因分析

(Ref: reference, where indicated gene was published as OA susceptibility gene; Pval: nominal P-value; FC: fold change; –: not detected on microarray).

NIAID Data Ecosystem60

Identification of AIA-related genes

关节炎基因表达

差异表达基因分析

To obtain AIA-related genes [the significant differentially expressed genes (DEGs) of AIA model group vs. Normal control group], the microarray analysis was carried out. 6 rat samples were randomly di

NIAID Data Ecosystem110

Identification of phase-specific arthritis-related genes in mice

关节炎基因表达

小鼠模型分子机制

Rheumatoid arthritis (RA), one of the most common polygenic diseases, is characterized by a chronic, progressive inflammation mainly in joints and has an unknown etiology. Numerous studies have reveal

NIAID Data Ecosystem60

Transcription profiling of human synovial fibroblasts from rheumatoid arthritis and osteoarthritis patients

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