Adjusted Associations between rs780094 and Study Outcomes in White Atherosclerosis Risk in Communities Study Participants.

*Note: Model 1 adjusted for age, sex, study center; model 2 adjusted for age, sex, study center, fasting glucose, fasting insulin, triglycerides. Metabolic syndrome was not adjusted for glucose and triglycerides in model 2. HOMA-IR, HOMA-B, and DM not adjusted for fasting glucose and insulin in model 2. All cross-sectional associations evaluated using baseline measurements (n = 10,601), except for 2 hr post-OGTT glucose (n = 7,073) and C-reactive protein (n = 8,131), which were only measured at visit 4. 935 participants out of 9,230 developed DM over mean follow-up of 8 years; 1,705 out of 10,600 developed CHD and 418 out of 10,600 experienced a stroke over mean follow-up of 15 years.