Part I: Proteomics Target Approach for Taxonomic and Sex Identification in Modern and Archaeological Enamel Caprines

. In this study, we applied proteomic analytical methods to modern caprine (sheep, Ovis aries and goat, Capra hircus) tooth enamel to establish a reliable method for identifying species-specific and sex-specific peptides. Utilizing single amino acid variations (SAAVs) in Enamelin (Enam) and Amelogenin (Amel) proteins, we developed a targeted parallel reaction monitoring (PRM) assay to identify molecular markers preserved in enamel of modern caprines