Mutations disrupting the reading frame of the UGT1A6 gene found in 18 different species of Felidae.

(+) and (-) denotes presence or absence of inactivating coding sequence mutation in that species UGT1A6 sequence.MYA - millions of years ago. bp - base pairs.1Nucleotide position relative to adenine (+1) of start codon ATG of human UGT1A6 exon1 (GenBank accession no.- M84130).2Felidae lineages and divergence dates used to estimate mutation fixation timing (in MYA) were derived from Table 1 in Johnson et al, 2005.