EGFR inhibitors resistance

NIAID Data Ecosystem2026-03-13 收录

化疗耐药机制

EGFR靶向治疗

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA831780 数据链接链接失效反馈

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To search for possible resistant mechanism to osimertinib, PC9 cells and their derived osimertinib-resistant PC9OR cells were sequenced using illumina HiSeq

创建时间：

2022-04-25

Gene expression profile of patient-derived head and neck squamous carcinoma cells subjected to different treatments.. Gene expression profile of patient-derived head and neck squamous carcinoma cells subjected to different treatments.

头颈部鳞状细胞癌基因

化疗耐药机制

In order to investigate the mechanisms underlying response and resistance towards treatment in HNSCC, we used low passage in vitro HNSCC cultures from two patients, namely SJG26 and SJG17. Both cultur

NIAID Data Ecosystem70

Additional file 3 of Adipocyte pyroptosis occurs in omental tumor microenvironment and is associated with chemoresistance of ovarian cancer

肿瘤微环境

化疗耐药机制

Additional file 3.

NIAID Data Ecosystem30

Gene expression of A204 parental and acquired resistant cells treated with Pazopanib, Dasatinib, and Sunitinib.. Homo sapiens

化疗耐药机制

恶性横纹肌肿瘤

Malignant rhadboid tumours (MRTs) are lethal paediatric cancers characterised by a deficiency in the SWI/SNF subunit SMARCB1. Here we employ an integrated molecular profiling and chemical biology appr

NIAID Data Ecosystem20

Loss of IFN-g signaling in tumor cells associates with primary resistance to anti-CTLA-4 therapy

化疗耐药机制

IFN-γ信号通路

"Antibody blockade of the inhibitory CTLA-4 pathway has led to clinical benefit in a subset of patients with metastatic melanoma. Anti-CTLA-4 enhances T cell responses, including production of IFN-?,

NIAID Data Ecosystem40

Breast Cancer Stem Cells Regulated Phenotypic Equilibrium Drives Tamoxifen Resistance

化疗耐药机制

干细胞微环境

Breast cancers consist of heterogeneous cellular subpopulations that differ in molecular properties and functional attributes. Cancer cells display phenotypic equilibrium between the stem-like and dif

NIAID Data Ecosystem20

EGFR inhibitors resistance

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