EGFR inhibitors resistance

NIAID Data Ecosystem2026-03-13 收录

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA831780

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To search for possible resistant mechanism to osimertinib, PC9 cells and their derived osimertinib-resistant PC9OR cells were sequenced using illumina HiSeq

创建时间：

2022-04-25

EGFR inhibitors resistance

To search for possible resistant mechanism to osimertinib, PC9 cells and their derived osimertinib-resistant PC9OR cells were sequenced using illumina HiSeq

NIAID Data Ecosystem20

Ability of the Met Kinase Inhibitor Crizotinib and New Generation EGFR Inhibitors to Overcome Resistance to EGFR Inhibitors

PurposeAlthough EGF receptor tyrosine kinase inhibitors (EGFR-TKI) have shown dramatic effects against EGFR mutant lung cancer, patients ultimately develop resistance by multiple mechanisms. We theref

Figshare2016-01-18 更新10

Characterization of the mechansims involved in resistance to EGFR inhibitors

We generated patient cSCC-derived xenografts (cSCC-PDXs) that recapitulate the histopathologic and molecular features of parental patient samples. Response to gefitinib treatment was tested in four in

NIAID Data Ecosystem20

Characterization of the mechansims involved in resistance to EGFR inhibitors. Characterization of the mechansims involved in resistance to EGFR inhibitors

NIAID Data Ecosystem40

Ability of the Met Kinase Inhibitor Crizotinib and New Generation EGFR Inhibitors to Overcome Resistance to EGFR Inhibitors

Purpose Although EGF receptor tyrosine kinase inhibitors (EGFR-TKI) have shown dramatic effects against EGFR mutant lung cancer, patients ultimately develop resistance by multiple mechanisms. We there

NIAID Data Ecosystem30