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An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation (CRISPRi screen)

NIAID Data Ecosystem2026-05-02 收录

非编码RNA功能

CRISPRi筛选

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE270859 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-04-15

非编码RNA功能

水稻耐旱分子机制

Additional file 4. The specific primer sequences for RLM-5’ RACE of target genes.

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Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

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Genes of CRISPR-Cas9 negative screening.

CRISPRi筛选

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We compared changes in sgRNA abundance between T24 cells challenged and unchallenged by CD8+ T cells, and then performed negative screening (p < 0.01, log2Fold change < −1.0, and good sgRNAs ≥ 5). (X

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Identification of gene expression in cells that may express micropeptide from RN7SL1. Identification of gene expression in cells that may express micropeptide from RN7SL1

非编码RNA功能

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RN7SL1 is a 299-base single-stranded RNA that binds to five SRP proteins and contributes to the generation of transmembrane and secretory proteins as a signal recognition particle. It theoretically po

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Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies. Mair et al.

干细胞鉴定

CRISPRi筛选

Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms,

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An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation (CRISPRi screen)

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