Cryo-EM structure of the complex of DNA, Ku70/80, and laXLF.

Cryo-EM structure of the complex of DNA, Ku70/80, and laXLF. Descriptor: (2S)-2-HYDROXYPROPANOIC ACID, DNA (5'-D(P*AP*GP*GP*TP*CP*GP*AP*CP*GP*AP*AP*TP*CP*GP*GP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*TP*GP*CP*CP*GP*AP*TP*TP*CP*GP*TP*CP*GP*AP*CP*CP*T)-3'), ... Authors: Liang, S. Deposit date: 2024-07-09 Release date: 2025-07-09 Last modified: 2025-07-30 Method: ELECTRON MICROSCOPY (3.46 Å) Cite: Lactylation of XLF promotes non-homologous end-joining repair and chemoresistance in cancer. Mol.Cell, 85, 2025