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Silver(I) and Copper(I) Cocatalyzed Tandem Reaction of 2‑Alkynylbenzaldoximes with Aldehydes or Alcohols: Approach to 4‑Carboxylated Isoquinolines

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NIAID Data Ecosystem2026-03-08 收录
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A novel and efficient route for the preparation of 4-carboxylated isoquinolines via a Ag­(I) and Cu­(I) cocatalyzed tandem reaction of 2-alkynylbenzaldoximes with aldehydes or alcohols in moderate to good yields is described. The reaction proceeds smoothly to produce C–N and C–O bonds in a one-pot procedure with structural complexity and molecular diversity.

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2014-09-05
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